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ea0099p515 | Pituitary and Neuroendocrinology | ECE2024

Body weight in acromegaly – does it make any difference?

Kaniuka-Jakubowska Sonia , higham claire , Davis Jessica , Kearney Tara , Loughrey Paul , Elamin Aisha , Flanagan Daniel , Kaszubowski Mariusz , Ayuk John , M Orme Steve , Wass John

Introduction: IGF-1 dependence on sex is a well-known fact; however, whether IGF-1 is also influenced by body weight is still questionable, and the mechanism of a potential relationship between GH, IGF-1 and body weight is not fully explained. The effect of gender (or rather oestrogens) on IGF-1 is visible in acromegaly - women are diagnosed at an older age than men (approximately 4 years) (potentially by suppressive effect on the axis of GH-IGF-1). The aim of the study was to...

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ea0099p404 | Late-Breaking | ECE2024

Weaning patients off long-term low dose prednisolone: an international survey of current endocrine practice

Lazarus Katharine , Eng Pei , Narula Kavita , Choudhury Sirazum , Martin Niamh , Wernig Florian , Papadopoulou Debbie , Tan Tricia , Elhassan Yasir , Mitchell Anna , Simpson Helen , Davis Jessica , Evans Roisin , Single Kate , Meeran Karim

Background: Prolonged glucocorticoid (GC) use is associated with significant morbidity and mortality, including the development of glucocorticoid-induced adrenal insufficiency (GI-AI). There is currently no consensus regarding testing or weaning of GCs prescribed for non-endocrine conditions.Aim: To assess the long-term GC weaning practice by endocrinologists in the UK and Southeast Asia.Methods: An anonymous survey was disseminate...

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Endocrine Abstracts

Body weight in acromegaly – does it make any difference?

Weaning patients off long-term low dose prednisolone: an international survey of current endocrine practice

BiosciAbstracts